Weak/Extensive Metabolizers, CYP2D6 The development of the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Close to 7% of the inhabitants has diminished exercise of the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme technique. These people are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, between other https://anner864rxc8.onzeblog.com/profile