Here, we display that conolidine, a all-natural analgesic alkaloid used in traditional Chinese medicine, targets ACKR3, thereby delivering additional evidence of the correlation between ACKR3 and ache modulation and opening different therapeutic avenues for that treatment method of Serious suffering. Natural ache aid without any opioids, no Negative effects? https://www.proleviate.com/post/conolidine-for-pain-relief