Background: The long-term prognosis for patients with osteosarcoma (OS) metastasis remains unfavourable. highlighting the urgent need for research that explores potential biomarkers using innovative methodologies. Methods: This study explored potential biomarkers for OS metastasis by analysing data from the Cancer Genome Atlas Program (TCGA) and Gene Expression Omnibus (GEO) databases... https://www.opheliasmuse.com/