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When an opiate binds as an agonist into the GPCR, there'll be considered a signaling cascade causing the inhibition of adenylate cyclase and calcium ion channels with the stimulation of potassium ion channels. The net effect of such variations is really a lowered intracellular cAMP and hyperpolarization in the neuronal https://opioids-and-benzodiazepin27271.wikijm.com/835706/the_5_second_trick_for_4_examples_of_opioids

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