The recognized effects of those PTMs on ATXN2’s operate and SCA2 pathogenesis continues to be constrained. In other polyQ conditions, several research suggested that proteolytic cleavage of polyQ proteins could Participate in a very important purpose in pathogenesis [36, 45]. Aligned with this strategy, the presence of the enriched 42 kDa https://fredp505aoa6.wikitron.com/user