Cyclosporine will enhance the level or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. fluconazole will boost the stage or result of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. nelfinavir will improve the amount or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabo... https://raymondj439wxw7.ziblogs.com/profile