Higher glucose inbound links to dysfunctions of glucose uptake and catabolism and induces substantial oxidative worry, dysfunction of endothelial cells. Higher hypertension causes cardiac and vascular damage. Central being overweight is connected with maldistribution of free of charge fatty acid, overproduction of inflammatory molecules, and leptin resistance [21]. e-Century Publishing https://www.directivepublications.org/journal-of-cardiovascular-diseases/