Ketoconazole Coadministration of bosentan one hundred twenty five mg twice everyday and ketoconazole, a strong CYP3A inhibitor, elevated the plasma concentrations of bosentan by approximately a hundred% in normal volunteers. No dose adjustment of bosentan is important, but increased results of bosentan really should be viewed as. Tend not to https://beauhylwi.blogscribble.com/26141784/facts-about-bosentan-revealed